AMELIORATION OF OBSESSIVE-COMPULSIVE DISORDER BY INTRACELLULAR ACIDIFICATION OF CORTICAL NEURONS WITH A PROTON PUMP INHIBITOR

Amelioration of obsessive-compulsive disorder by intracellular acidification of cortical neurons with a proton pump inhibitor

Abstract Obsessive-compulsive disorder (OCD) is a highly prevalent neuropsychiatric disorder poorly controlled with pharmacological treatment Nitric Oxide because of the wide variation in symptom patterns.We analysed real-world data on adverse self-reports and insurance claims to identify a novel therapeutic target for OCD.We found that dopamine D2

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Implementation and validation of an in-house combined fluorescein/media-fill test to qualify radiopharmacy operators

Abstract Background The purpose of this work was to design, validate and implement a media-fill test combined with fluorescein (MFT-F) for the specific qualification and training of radiopharmacy operators, in accordance with United States Pharmacopeia General Chapter 797 and European Good Manufacturing Practices.MFT-F was embedded in the quality m

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